Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5166002 | 0.95 | CA12 (0.43) | CA12CA9PARGVCAM1MPO | |
| SCHEMBL2389058 | 0.86 | CA12 (0.64) | CA12CA9LMNANPSR1PARP1 | |
| SCHEMBL9258900 | 0.86 | CA12 (0.43) | CA12CA9ALDH1A1MAPTPTGS2 | |
| SCHEMBL9260491 | 0.86 | CA12 (0.60) | CA12CA9 | |
| SCHEMBL5167851 | 0.83 | CA9 (0.40) | CA12CA9ALDH1A1LMNAMAPT | |
| SCHEMBL5167310 | 0.81 | ALDH1A1 (0.40) | CA12CA9ALDH1A1LMNAMAPT | |
| SCHEMBL5165208 | 0.81 | NQO2 (0.42) | CA12CA9MPOALDH1A1LMNA | |
| SCHEMBL5455598 | 0.80 | GRIK1 (0.51) | CA12CA9 | |
| SCHEMBL5179666 | 0.80 | CA12 (0.38) | CA12CA9ALDH1A1LMNAMAPT | |
| SCHEMBL5182233 | 0.79 | MAPT (0.41) | CA12CA9GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |