Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 9/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255356 | 1.00 | PLK1 (0.44) | PLK1CYSLTR2CYSLTR1GAARAB9A | |
| SCHEMBL9254823 | 0.89 | CYSLTR2 (0.52) | PLK1CYSLTR2CYSLTR1GAARAB9A | |
| SCHEMBL9713817 | 0.87 | PLK1 (0.59) | PLK1CYSLTR2CYSLTR1GAA | |
| SCHEMBL9857433 | 0.79 | SMPD1 (0.52) | PLK1CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL9132501 | 0.78 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1 | |
| SCHEMBL9132741 | 0.78 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1 | |
| SCHEMBL9257603 | 0.76 | CYSLTR1 (0.51) | PLK1CYSLTR2CYSLTR1RAB9ANPC1 | |
| SCHEMBL9133034 | 0.75 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1 | |
| SCHEMBL9551229 | 0.74 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 | |
| SCHEMBL10868241 | 0.74 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446058-A | Leukotriene antagonists, 5-alpha-reductase inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | claimed |
| EP-0463638-B1 | Aminophenyl derivatives | ONO PHARMACEUTICAL CO (JP) | 1995-05-24 | — | — | EP | claimed |
| EP-0463638-A1 | Aminophenyl derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-01-02 | — | — | EP | claimed |