Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 4/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 10/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9857433 | 0.90 | SMPD1 (0.52) | PLK1CYSLTR2CYSLTR1 | |
| SCHEMBL9132741 | 0.90 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1CACNA1HCACNA1B | |
| SCHEMBL9132501 | 0.90 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1CACNA1HCACNA1B | |
| SCHEMBL9257603 | 0.88 | CYSLTR1 (0.51) | PLK1CYSLTR2CYSLTR1CACNA1HCACNA1B | |
| SCHEMBL9254823 | 0.88 | CYSLTR2 (0.52) | PLK1CYSLTR2CYSLTR1GAACACNA1H | |
| SCHEMBL9254816 | 0.87 | PLK1 (0.44) | PLK1CYSLTR2CYSLTR1GAA | |
| SCHEMBL9255356 | 0.87 | PLK1 (0.44) | PLK1CYSLTR2CYSLTR1GAA | |
| SCHEMBL9133034 | 0.87 | PLK1 (0.52) | PLK1CYSLTR2CYSLTR1CACNA1HCACNA1B | |
| SCHEMBL10721101 | 0.84 | NR1H4 (0.59) | PLK1CYSLTR2CYSLTR1 | |
| SCHEMBL9135604 | 0.84 | CACNA1H (0.49) | PLK1CYSLTR2CYSLTR1CACNA1HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | claimed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | claimed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | claimed |
| US-5140046-A | Slow reacting substance of anaphylaxis antagonists | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-18 | — | — | US | disclosed |
| US-5116853-A | SRS-Antagonist, Antiallergens | MASE TOSHIYASU (JP) | 1992-05-26 | — | — | US | disclosed |
| US-4994479-A | Antagonists of SRS-A(slow reacting substance of anaphylaxis); antiallergens, antiischemic agents | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0218728-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005779-A1 | PHENYLENE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1986-10-09 | — | — | WO | disclosed |