Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACSS2 | Q9NR19 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863519 | 0.92 | HDAC1 (0.52) | NPC1RAB9ATMPRSS15HDAC1HDAC8 | |
| Hydrochloric Acid SCHEMBL9255053 | 0.91 | HDAC1 (0.51) | NPC1RAB9ATMPRSS15HDAC1HDAC8 | |
| SCHEMBL9252708 | 0.90 | CHEK2 (0.51) | CHEK2BMPR2F10F2PLG | |
| SCHEMBL9255062 | 0.87 | CHEK2 (0.40) | CHEK2F10F2PLGPLAU | |
| SCHEMBL9251150 | 0.87 | HDAC1 (0.50) | RAB9AHDAC1HDAC8HDAC6MAPT | |
| SCHEMBL9255533 | 0.86 | NPC1 (0.40) | CHEK2F2NPC1RAB9ATMPRSS15 | |
| Hydrochloric Acid SCHEMBL8863892 | 0.86 | HDAC1 (0.49) | RAB9AHDAC1HDAC8HDAC6MAPT | |
| SCHEMBL9249905 | 0.85 | CHEK2 (0.39) | CHEK2NPC1RAB9ATMPRSS15HDAC1 | |
| SCHEMBL9571166 | 0.85 | HDAC1 (0.40) | CHEK2BMPR2F10F2PLG | |
| SCHEMBL9251884 | 0.85 | HDAC1 (0.50) | F10F2PLGHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |