Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249490 | 0.92 | HDAC1 (0.56) | ITGB3ITGA2BF10F2PLG | |
| SCHEMBL9254880 | 0.90 | CHEK2 (0.49) | CHEK2ITGB3ITGA2BF10F2 | |
| SCHEMBL9252280 | 0.86 | ITGB3 (0.45) | CHEK2ITGB3ITGA2BF10F2 | |
| SCHEMBL9249572 | 0.86 | ITGB3 (0.56) | ITGB3ITGA2BF2HDAC1HDAC8 | |
| SCHEMBL9247795 | 0.85 | ITGB3 (0.44) | CHEK2ITGB3ITGA2BF2HDAC1 | |
| SCHEMBL9254520 | 0.85 | ITGB3 (0.44) | CHEK2ITGB3ITGA2BF2HDAC1 | |
| SCHEMBL9249022 | 0.85 | ITGB3 (0.44) | CHEK2ITGB3ITGA2BF2HDAC1 | |
| SCHEMBL9252571 | 0.84 | ITGB3 (0.45) | CHEK2ITGB3ITGA2BF10F2 | |
| SCHEMBL9255526 | 0.84 | ITGB3 (0.43) | CHEK2ITGB3ITGA2BF10F2 | |
| SCHEMBL9252912 | 0.84 | ITGB3 (0.43) | CHEK2ITGB3ITGA2BF2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |