Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 2/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 18/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 3/20 | 0.56 |
| ▸ | PDE4A | P27815 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528251 | 0.83 | ABCB11 (0.73) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8528403 | 0.77 | ABCB11 (0.93) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8527365 | 0.76 | ABCB11 (0.92) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL7836713 | 0.76 | ABCB11 (0.62) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL5397349 | 0.75 | ABCB11 (0.72) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7829287 | 0.75 | ABCB11 (0.61) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| SCHEMBL8528222 | 0.75 | ABCB11 (0.74) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7791110 | 0.75 | ABCB11 (0.71) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL7842790 | 0.74 | ADRB2 (0.80) | ABCB11ADRB2ADRB1DRD2PDE4A | |
| Hydrochloric Acid SCHEMBL8532220 | 0.74 | ABCB11 (0.73) | ABCB11ADRB2ADRB1DRD2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649418-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | Astra Pharmaceuticals Limited (GB) | 1995-04-26 | — | — | EP | claimed |
| WO-1993024473-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | FISONS PLC (GB) | 1993-12-09 | — | — | WO | claimed |