Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877100 | 0.76 | F2 (0.40) | F2LMNACES1TSHRCES2 | |
| SCHEMBL3990387 | 0.75 | TSHR (0.34) | F2LMNACES1TSHRCES2 | |
| SCHEMBL9719608 | 0.74 | CES2 (0.42) | F2LMNACES1TSHRCES2 | |
| SCHEMBL10179795 | 0.70 | F2 (0.41) | F2LMNACES1TSHRCES2 | |
| SCHEMBL10420256 | 0.69 | CES1 (0.43) | F2LMNACES1TSHRCES2 | |
| SCHEMBL285854 | 0.69 | CES1 (0.43) | F2LMNACES1TSHRCES2 | |
| SCHEMBL703632 | 0.68 | CES1 (0.50) | F2LMNACES1TSHRCES2 | |
| SCHEMBL3929950 | 0.67 | CES1 (0.47) | F2LMNACES1TSHRCES2 | |
| SCHEMBL525632 | 0.67 | — | — | |
| SCHEMBL2234110 | 0.67 | CES1 (0.47) | F2LMNACES1TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428709-B1 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS | DOW CHEMICAL CO (US) | 1995-05-24 | — | — | EP | disclosed |
| EP-0428709-A1 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS. | DOW CHEMICAL CO (US) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015042-A2 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS | THE DOW CHEMICAL COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |