Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.60 |
| ▸ | BCHE | P06276 | 7/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.59 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.51 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.51 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.51 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.51 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.51 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.51 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | FABP1 | P07148 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260059 | 0.90 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9255193 | 0.90 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9255981 | 0.90 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9256157 | 0.90 | ACHE (0.60) | ACHEBCHEGRIN1GRIN2ACHRM1 | |
| SCHEMBL9255203 | 0.88 | ACHE (0.56) | ACHEALDH1A1 | |
| SCHEMBL9252885 | 0.80 | MAPT (0.56) | ACHEBCHEALDH1A1TSHR | |
| SCHEMBL9256559 | 0.80 | MAPT (0.56) | ACHEBCHEALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL9256019 | 0.79 | MAPT (0.55) | ACHEBCHE | |
| SCHEMBL9252756 | 0.78 | ACHE (0.51) | ACHEBCHEALDH1A1TSHR | |
| SCHEMBL10699056 | 0.76 | ACHE (0.60) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |