Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 4/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SNCA | P37840 | 3/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5682532 | 0.74 | SHBG (0.48) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL5682603 | 0.74 | SHBG (0.48) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL8518161 | 0.74 | SHBG (0.48) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL3845915 | 0.72 | AKR1C3 (0.39) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL7587734 | 0.69 | SHBG (0.64) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL29446097 | 0.68 | SHBG (0.70) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL13725675 | 0.68 | SHBG (0.70) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL975788 | 0.68 | SHBG (0.70) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL11096655 | 0.68 | SHBG (0.70) | SHBGESR1ESR2LMNAHIF1A | |
| SCHEMBL30887214 | 0.68 | SHBG (0.70) | SHBGESR1ESR2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418227-A | 14,16β-ethano-15β, 16(1)-cyclo-14β-estra-1,3,5(10)-trienes | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-05-23 | — | — | US | disclosed |