Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255626 | 1.00 | KMT2A (0.49) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL16019162 | 0.82 | RAB9A (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17926074 | 0.82 | RAB9A (0.47) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4572964 | 0.80 | GLA (0.38) | KMT2AMEN1ALDH1A1RAB9AHCAR2 | |
| SCHEMBL4572963 | 0.80 | GLA (0.38) | KMT2AMEN1ALDH1A1RAB9AHCAR2 | |
| SCHEMBL2522171 | 0.78 | HCAR2 (0.48) | KMT2ACA12CA1CA2TYR | |
| SCHEMBL2522174 | 0.78 | HCAR2 (0.48) | KMT2ACA12CA1CA2TYR | |
| SCHEMBL18985284 | 0.77 | CCNC (0.41) | KMT2AMEN1ALDH1A1RAB9AHCAR2 | |
| SCHEMBL6297810 | 0.76 | PIK3CD (0.37) | RAB9ASMN1; SMN2HPGDNLRP3 | |
| SCHEMBL3945104 | 0.76 | CCNC (0.36) | ALDH1A1RAB9AMAPTLMNACCNC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |