Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2522171 | 0.82 | HCAR2 (0.48) | NLRP3HCAR2PIM1RAB9ANPC1 | |
| SCHEMBL2522174 | 0.82 | HCAR2 (0.48) | NLRP3HCAR2PIM1RAB9ANPC1 | |
| SCHEMBL4395610 | 0.82 | — | — | |
| SCHEMBL4572963 | 0.81 | GLA (0.38) | NLRP3HCAR2PIM1RAB9ANPC1 | |
| SCHEMBL4572964 | 0.81 | GLA (0.38) | NLRP3HCAR2PIM1RAB9ANPC1 | |
| SCHEMBL9255626 | 0.77 | KMT2A (0.49) | CCNCCDK8NLRP3HCAR2RAB9A | |
| SCHEMBL9255628 | 0.77 | KMT2A (0.49) | CCNCCDK8NLRP3HCAR2RAB9A | |
| SCHEMBL6297811 | 0.77 | PIK3CD (0.37) | NLRP3PIM1RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL1556671 | 0.74 | PFKFB3 (0.53) | SMN1; SMN2ALDH1A1MEN1PSMD14LMNA | |
| SCHEMBL17926074 | 0.73 | RAB9A (0.47) | CCNCCDK8HCAR2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017102014-A1 | PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE | UNIVERSITE D'AIX-MARSEILLE (FR) | 2017-06-22 | — | — | WO | disclosed |