Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.59 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957832 | 0.84 | LOXL2 (0.58) | KCNH2LOXL2TSHRIDO1 | |
| SCHEMBL16572121 | 0.83 | KCNH2 (0.57) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| SCHEMBL4274526 | 0.83 | KCNH2 (0.56) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| SCHEMBL335044 | 0.81 | LOXL2 (0.69) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| SCHEMBL9628232 | 0.81 | KCNH2 (0.76) | KCNH2LOXL2TSHRKCNJ1SIGMAR1 | |
| SCHEMBL3157762 | 0.81 | KCNH2 (0.71) | KCNH2LOXL2TSHRKCNJ1SIGMAR1 | |
| Bromide SCHEMBL11379599 | 0.80 | LOXL2 (0.67) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| SCHEMBL19874575 | 0.80 | LOXL2 (0.67) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| Ammonia Solution, Strong SCHEMBL21518028 | 0.80 | LOXL2 (0.67) | KCNH2LOXL2TSHRKCNJ1IDO1 | |
| Hydrochloric Acid SCHEMBL115247 | 0.80 | LOXL2 (0.67) | KCNH2LOXL2TSHRKCNJ1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653941-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994000145-A1 | TARGETED DELIVERY OF GROWTH FACTORS FOR BONE REGENERATION | THE DOW CHEMICAL COMPANY (US) | 1994-01-06 | — | — | WO | disclosed |