Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210655 | 0.91 | TP53 (0.39) | TP53MAPTLMNAALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL9219227 | 0.90 | TP53 (0.39) | TP53MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9256673 | 0.87 | TP53 (0.39) | TP53MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL9255403 | 0.86 | MAPT (0.38) | TP53MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9213292 | 0.86 | MAPT (0.38) | TP53MAPTLMNATSHRALDH1A1 | |
| SCHEMBL9215578 | 0.85 | MAPT (0.37) | TP53MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9207052 | 0.85 | TP53 (0.38) | TP53MAPTLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9255151 | 0.85 | TP53 (0.40) | TP53MAPTLMNASMN1; SMN2TSHR | |
| SCHEMBL9259987 | 0.85 | TP53 (0.50) | TP53MAPTLMNAALDH1A1HPGD | |
| SCHEMBL9260614 | 0.84 | MAPT (0.40) | TP53MAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475000-A | Antiulcer agents | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-12-12 | — | — | US | disclosed |
| US-5384406-A | Hydrolysis resistant; agriculture chemical anions | ISP INVESTMENTS INC. (US) | 1995-01-24 | — | — | US | disclosed |
| WO-1993004065-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO-[1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-03-04 | — | — | WO | disclosed |