Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | QPCT | Q16769 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255747 | 0.86 | TP53 (0.40) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9210655 | 0.84 | TP53 (0.39) | MAPTTP53LMNANPSR1KDM4E | |
| Hydrochloric Acid SCHEMBL9219227 | 0.83 | TP53 (0.39) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9256673 | 0.83 | TP53 (0.39) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9213292 | 0.83 | MAPT (0.38) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9215578 | 0.82 | MAPT (0.37) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9259987 | 0.81 | TP53 (0.50) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9260614 | 0.80 | MAPT (0.40) | MAPTTP53LMNANPSR1KDM4E | |
| SCHEMBL9262148 | 0.80 | LMNA (0.44) | MAPTTP53LMNAHDAC8NPC1 | |
| SCHEMBL9255151 | 0.79 | TP53 (0.40) | MAPTTP53LMNAKDM4EHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475000-A | Antiulcer agents | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-12-12 | — | — | US | disclosed |