Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.41 |
| ▸ | WNT1 | P04628 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.38 |
| ▸ | CLK2 | P49760 | 3/20 | 0.38 |
| ▸ | CLK3 | P49761 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259624 | 0.90 | CHRNA7 (0.46) | CHRNA7DYRK1AWNT1GSK3BCSF1R | |
| SCHEMBL8533375 | 0.88 | CHRNA7 (0.47) | CHRNA7MAPTACACB | |
| SCHEMBL9250939 | 0.86 | CHRNA7 (0.50) | CHRNA7DYRK1AWNT1GSK3BCSF1R | |
| SCHEMBL8532209 | 0.85 | CHRNA7 (0.44) | CHRNA7CSF1RFLT3MAPTACACB | |
| SCHEMBL9262940 | 0.84 | CHRNA7 (0.44) | CHRNA7MAPT | |
| SCHEMBL9253063 | 0.83 | KDM1A (0.45) | CHRNA7DYRK1AWNT1GSK3BCSF1R | |
| SCHEMBL8533987 | 0.83 | GPR119 (0.46) | CHRNA7ACACB | |
| SCHEMBL15253234 | 0.82 | CHRNA7 (0.45) | CHRNA7CSF1RFLT3ACACB | |
| SCHEMBL9259070 | 0.82 | DYRK1A (0.44) | CHRNA7DYRK1AWNT1GSK3BCSF1R | |
| SCHEMBL9255822 | 0.82 | CHRNA7 (0.36) | CHRNA7DYRK1AWNT1GSK3BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069917-A1 | BICYCLIC GPR119 MODULATORS | LUPIN LIMITED (IN) | 2012-05-31 | — | — | WO | disclosed |