Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS15 | P98073 | 7/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255591 | 0.91 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL9253863 | 0.89 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BADORA2AADORA2B | |
| SCHEMBL9256102 | 0.88 | ITGB3 (0.37) | TMPRSS15ITGB3ITGA2BADORA2AADORA2B | |
| SCHEMBL9251162 | 0.88 | TMPRSS15 (0.36) | TMPRSS15ITGB3ITGA2BADORA2AADORA2B | |
| SCHEMBL9255320 | 0.86 | TMPRSS15 (0.35) | TMPRSS15ITGB3ITGA2BMAPTSMN1; SMN2 | |
| SCHEMBL9251469 | 0.83 | TMPRSS15 (0.37) | TMPRSS15ITGB3ITGA2BF10 | |
| SCHEMBL9255743 | 0.82 | ITGB3 (0.40) | TMPRSS15ITGB3ITGA2B | |
| SCHEMBL9251097 | 0.81 | TMPRSS15 (0.40) | TMPRSS15ITGB3ITGA2BMAPTSMN1; SMN2 | |
| SCHEMBL9251145 | 0.80 | MAPT (0.37) | TMPRSS15ITGB3ITGA2BADORA2AADORA2B | |
| SCHEMBL9251249 | 0.79 | ITGB3 (0.42) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |