Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.63 |
| ▸ | BCHE | P06276 | 12/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261162 | 0.95 | ACHE (0.65) | ACHEBCHEAPP | |
| SCHEMBL9257365 | 0.91 | ACHE (0.61) | ACHEBCHEAPP | |
| SCHEMBL9252813 | 0.86 | ACHE (0.64) | ACHEBCHEAPP | |
| SCHEMBL9257198 | 0.85 | ACHE (0.47) | ACHEBCHEAPP | |
| SCHEMBL9257288 | 0.84 | ACHE (0.68) | ACHEBCHEAPP | |
| SCHEMBL9261779 | 0.83 | ACHE (0.48) | ACHEBCHEAPP | |
| SCHEMBL9255949 | 0.83 | ACHE (0.67) | ACHEBCHE | |
| Hydrochloric Acid SCHEMBL9257222 | 0.83 | ACHE (0.66) | ACHEBCHEAPP | |
| SCHEMBL9257175 | 0.82 | ACHE (0.69) | ACHEBCHE | |
| SCHEMBL9255906 | 0.80 | ACHE (0.50) | ACHEBCHEAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |