Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 9/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9257222 | 0.99 | ACHE (0.66) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9257175 | 0.99 | ACHE (0.69) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9260517 | 0.96 | ACHE (0.70) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9261331 | 0.93 | ACHE (0.68) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9257288 | 0.92 | ACHE (0.68) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9261203 | 0.88 | ACHE (0.71) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9253349 | 0.87 | ACHE (0.58) | ACHEKDM4EMEN1HTTKMT2A | |
| SCHEMBL9257365 | 0.85 | ACHE (0.61) | ACHEBCHE | |
| SCHEMBL9255970 | 0.83 | ACHE (0.63) | ACHEBCHE | |
| SCHEMBL9252705 | 0.83 | ACHE (0.65) | ACHEMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |
| EP-0282959-A2 | Substituted 9-amino-tetrahydro-acridines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1988-09-21 | — | — | EP | disclosed |