Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12807323 | 0.77 | HCAR2 (0.46) | LMNAALOX5KMT2AHCAR2CYP1A2 | |
| SCHEMBL20538944 | 0.76 | LMNA (0.43) | LMNAKMT2AMEN1POLBCYP1A2 | |
| SCHEMBL652267 | 0.76 | HTT (0.38) | LMNACYP1A2CYP2D6SMN1; SMN2CHRM2 | |
| SCHEMBL9256016 | 0.76 | LMNA (0.45) | LMNAALOX5KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL2701953 | 0.75 | HTT (0.42) | LMNAKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL9667401 | 0.73 | POLB (0.47) | ALOX5POLBGPR88 | |
| SCHEMBL11667108 | 0.73 | CYP1A2 (0.41) | LMNAALOX5KMT2AHCAR2CYP1A2 | |
| SCHEMBL4561510 | 0.73 | HCAR2 (0.45) | LMNAALOX5KMT2AHCAR2CYP1A2 | |
| SCHEMBL7035274 | 0.71 | CYP1A2 (0.44) | LMNAALOX5HCAR2CYP1A2CYP2D6 | |
| SCHEMBL7035272 | 0.71 | CYP1A2 (0.44) | LMNAALOX5HCAR2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649418-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | Astra Pharmaceuticals Limited (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993024473-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | FISONS PLC (GB) | 1993-12-09 | — | — | WO | disclosed |