Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269816 | 0.82 | KMT2A (0.55) | LMNAKMT2ATDP1NPC1RAB9A | |
| SCHEMBL8668873 | 0.79 | PPARG (0.46) | LMNAPTGESALOX5PPARGTDP1 | |
| SCHEMBL9667408 | 0.78 | PPARG (0.56) | LMNAPTGESALOX5PPARGCTSK | |
| SCHEMBL531070 | 0.76 | CA1 (0.39) | PTGESALOX5PPARGCTSKNPC1 | |
| SCHEMBL9256023 | 0.76 | LMNA (0.38) | LMNAKMT2AALOX5SMN1; SMN2MAPK1 | |
| SCHEMBL16673082 | 0.75 | LMNA (0.47) | LMNAKMT2APTGESALOX5PPARG | |
| SCHEMBL4447170 | 0.75 | SMN1; SMN2 (0.60) | LMNAKMT2APPARGNPC1RAB9A | |
| SCHEMBL6322871 | 0.74 | CTSK (0.46) | PTGESALOX5PPARGCTSKTDP1 | |
| SCHEMBL5038179 | 0.74 | SLC1A3 (0.49) | LMNAKMT2APPARGTDP1ALDH1A1 | |
| SCHEMBL4561509 | 0.74 | EPHX1 (0.49) | LMNAKMT2APTGESALOX5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649418-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | Astra Pharmaceuticals Limited (GB) | 1995-04-26 | — | — | EP | disclosed |
| WO-1993024473-A1 | 7-(2-AMINOETHYL)-BENZOTHIAZOLONES | FISONS PLC (GB) | 1993-12-09 | — | — | WO | disclosed |