Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 8/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252705 | 0.90 | ACHE (0.65) | TP53GAASMN1; SMN2LMNAHTT | |
| SCHEMBL10699871 | 0.89 | ACHE (0.65) | TP53GAASMN1; SMN2LMNAGFER | |
| SCHEMBL9253451 | 0.89 | ACHE (0.67) | TP53GAASMN1; SMN2LMNAHTT | |
| SCHEMBL9261276 | 0.85 | ACHE (0.68) | TP53GAASMN1; SMN2LMNAHTT | |
| SCHEMBL9252906 | 0.84 | ACHE (0.60) | TP53GAASMN1; SMN2LMNAHTT | |
| SCHEMBL9257198 | 0.82 | ACHE (0.47) | TP53SMN1; SMN2ACHEKMT2ANPSR1 | |
| SCHEMBL9253349 | 0.80 | ACHE (0.58) | HTTACHEKMT2AMEN1BCHE | |
| SCHEMBL9261779 | 0.80 | ACHE (0.48) | TP53SMN1; SMN2ACHEKMT2ANPSR1 | |
| SCHEMBL9257365 | 0.79 | ACHE (0.61) | ACHEBCHE | |
| SCHEMBL9263594 | 0.77 | ACHE (0.69) | TP53GAASMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |