Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.58 |
| ▸ | BCHE | P06276 | 6/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260517 | 0.91 | ACHE (0.70) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9257175 | 0.88 | ACHE (0.69) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9255949 | 0.87 | ACHE (0.67) | ACHEBCHEBACE1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9257222 | 0.86 | ACHE (0.66) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9257288 | 0.85 | ACHE (0.68) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9261203 | 0.83 | ACHE (0.71) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9252813 | 0.83 | ACHE (0.64) | ACHEBCHECYP1A2 | |
| SCHEMBL10696834 | 0.81 | ACHE (0.62) | ACHEBCHEBACE1KDM4EMEN1 | |
| SCHEMBL9261162 | 0.81 | ACHE (0.65) | ACHEBCHECYP1A2 | |
| SCHEMBL9256060 | 0.80 | TP53 (0.60) | ACHEBCHEMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |