Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254933 | 0.81 | KMT2A (0.51) | KMT2ATSHRSMN1; SMN2AIMP2TDP1 | |
| SCHEMBL21213968 | 0.76 | AIMP2 (0.58) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL9259044 | 0.76 | KMT2A (0.61) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL18171334 | 0.75 | AIMP2 (0.81) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| Hydrochloric Acid SCHEMBL18171335 | 0.74 | AIMP2 (0.80) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL3355450 | 0.74 | KMT2A (0.73) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL3359550 | 0.73 | AIMP2 (0.67) | KMT2ATSHRGAAAIMP2POLB | |
| SCHEMBL3384086 | 0.72 | SIRT2 (0.52) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL25337487 | 0.71 | AIMP2 (1.00) | KMT2ATSHRSMN1; SMN2GAAAIMP2 | |
| SCHEMBL3359404 | 0.71 | KMT2A (0.57) | KMT2ATSHRSMN1; SMN2GAAAIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |