Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256464 | 0.81 | KMT2A (0.59) | KMT2ATSHRALDH1A1SMN1; SMN2PKM | |
| SCHEMBL9261915 | 0.75 | KDM4E (0.52) | KMT2ACYP2C19ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9259044 | 0.73 | KMT2A (0.61) | KMT2ATSHRALDH1A1SMN1; SMN2AIMP2 | |
| SCHEMBL9262598 | 0.73 | CYP2C19 (0.48) | KMT2ACYP2C19ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL9264486 | 0.72 | MEN1 (0.48) | KMT2ATSHRCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL9308618 | 0.71 | KDM4E (0.53) | KMT2ATSHRCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL9307946 | 0.70 | ALDH1A1 (0.49) | KMT2ATSHRCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL9309115 | 0.70 | ALDH1A1 (0.49) | KMT2ATSHRCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL28298203 | 0.70 | CHRM2 (0.79) | KMT2ATSHRCYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL9410571 | 0.69 | ALDH1A1 (0.54) | KMT2ACYP2C19ALDH1A1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | claimed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |