Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256464 | 0.76 | KMT2A (0.59) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL16601599 | 0.75 | ALDH1A1 (0.54) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7978591 | 0.75 | KMT2A (0.75) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9259654 | 0.74 | POLB (0.53) | KMT2ATSHRALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13962145 | 0.74 | ALDH1A1 (0.53) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9254933 | 0.73 | KMT2A (0.51) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13341114 | 0.72 | ALDH1A1 (0.51) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9260735 | 0.72 | POLB (0.76) | KMT2AALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL9259508 | 0.72 | CYP3A4 (0.47) | ALDH1A1SMN1; SMN2HPGDPOLBCHRNB4 | |
| SCHEMBL13202892 | 0.71 | ALDH1A1 (0.76) | KMT2ATSHRAIMP2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |
| EP-0624582-A1 | Substituted benzodioxine, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-11-17 | — | — | EP | disclosed |