Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4793706 | 0.99 | HPGD (0.50) | HPGDALDH1A1KDM4EHSD17B10SLC6A5 | |
| SCHEMBL16264683 | 0.91 | SLC6A5 (0.49) | HPGDALDH1A1KDM4ESLC6A5AKR1B1 | |
| SCHEMBL31376614 | 0.91 | MEN1 (0.50) | HPGDALDH1A1SLC6A5AKR1B1ACHE | |
| SCHEMBL8561824 | 0.89 | SLC6A5 (0.47) | HPGDALDH1A1KDM4ESLC6A5AKR1B1 | |
| SCHEMBL16264684 | 0.86 | SLC6A5 (0.45) | HPGDALDH1A1SLC6A5AKR1B1ACHE | |
| SCHEMBL8563163 | 0.86 | MEN1 (0.48) | ALDH1A1SLC6A5AKR1B1ACHEMEN1 | |
| SCHEMBL8566270 | 0.84 | GAA (0.47) | ALDH1A1KDM4ESLC6A5AKR1B1MEN1 | |
| Hydrochloric Acid SCHEMBL8561026 | 0.84 | KDM4E (0.45) | HPGDALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL17984953 | 0.84 | SLC6A5 (0.54) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL16264682 | 0.84 | SLC6A5 (0.54) | ALDH1A1KDM4ESLC6A5AKR1B1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5424433-A | Benzodiazepine receptor agonist | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1995-06-13 | — | — | US | claimed |