Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256480 | 0.91 | HPGD (0.51) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4793706 | 0.89 | HPGD (0.50) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL31376614 | 0.88 | MEN1 (0.50) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL8561824 | 0.86 | SLC6A5 (0.47) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL8563163 | 0.86 | MEN1 (0.48) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL8628851 | 0.84 | SLC6A5 (0.41) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL16264684 | 0.84 | SLC6A5 (0.45) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL8567999 | 0.83 | SLC6A5 (0.43) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL8566446 | 0.82 | SLC6A5 (0.42) | SLC6A5AKR1B1ACHEMEN1KMT2A | |
| SCHEMBL16264682 | 0.82 | SLC6A5 (0.54) | SLC6A5AKR1B1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9162983-B2 | Reactivators of organophosphorous inhibited acetylcholinesterase | SOUTHWEST RESEARCH INSTITUTE (US) | 2015-10-20 | — | — | US | disclosed |
| US-20140350262-A1 | Reactivators Of Organophosphorous Inhibited Acetylcholinesterase | SOUTHWEST RESEARCH INSTITUTE (US) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350262-A1 | Reactivators Of Organophosphorous Inhibited Acetylcholinesterase | ACHE, BCHE, CHAT | SLC6A5 2860/4885AKR1B1 1445/4885ACHE 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.