Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256476 | 1.00 | PRMT6 (0.38) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL9259057 | 0.82 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL9259049 | 0.82 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL27343281 | 0.76 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL9251449 | 0.76 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL27343282 | 0.76 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL9251453 | 0.76 | PRMT6 (0.44) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 | |
| SCHEMBL9248312 | 0.73 | SQLE (0.43) | — | |
| SCHEMBL9248304 | 0.73 | SQLE (0.43) | — | |
| SCHEMBL9254817 | 0.71 | PRMT6 (0.40) | PRMT6CYP2A6CYP2B6CYP2E1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |