Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4426319 | 0.80 | MMP8 (0.76) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL12963375 | 0.75 | PKM (0.58) | MMP8PKMALDH1A1KDM4EMEN1 | |
| SCHEMBL8158730 | 0.74 | MMP8 (0.53) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL6883494 | 0.74 | CYP4F2 (0.37) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL1036163 | 0.73 | PKM (0.50) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL996813 | 0.73 | MMP8 (0.71) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL7512223 | 0.71 | MMP8 (0.52) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL17035645 | 0.70 | MMP8 (0.53) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL334816 | 0.69 | MMP8 (0.56) | MMP8PKMCYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL13662635 | 0.69 | PKM (0.43) | MMP8PKMCYP4F2CYP4A11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463085-A | Synthesis method of physiologically active delta-lactone | NITTO DENKO CORPORATION (JP) | 1995-10-31 | — | — | US | claimed |
| JP-6345751-A | — | — | None | — | — | JP | disclosed |
| US-5463085-A | Synthesis method of physiologically active delta-lactone | NITTO DENKO CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| JP-H06345751-A | SYNTHESIS OF BIOACTIVE DELTA-LACTONE | NITTO DENKO CORP | 1994-12-20 | — | — | JP | disclosed |