SCHEMBL9256608

SCHEMBL9256608

O=C(Cl)[C@@H]1CCCN1C(=O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ACE P12821 3/20 0.33
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA9 Q16790 1/20 0.32
ELANE P08246 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11644333 0.90 LMNA (0.40) LMNACYP2C19HSD17B10ACECA12
SCHEMBL11650734 0.85 LMNA (0.53) LMNACYP2C19HSD17B10ACE
SCHEMBL11650731 0.85 LMNA (0.53) LMNACYP2C19HSD17B10ACE
SCHEMBL11649747 0.84 HSD17B10 (0.38) LMNACYP2C19HSD17B10ACECA12
SCHEMBL7333354 0.83 LMNA (0.41) LMNACYP2C19HSD17B10ACECA12
SCHEMBL247604 0.83 LMNA (0.41) LMNACYP2C19HSD17B10ACECA12
SCHEMBL2036130 0.83 LMNA (0.41) LMNACYP2C19HSD17B10ACECA12
SCHEMBL4586170 0.79 LMNA (0.50) LMNACYP2C19HSD17B10ACE
SCHEMBL28211348 0.74 ACE (0.43) ACECA12CA1CA2CA9
SCHEMBL15093294 0.74 DPP4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143839-A Water-soluble near infrared fluorescent molecular probe for detecting alkaline phosphatase as well as preparation method and application thereof 湖南超亟检测技术有限责任公司 2023-05-23 CN claimed
EP-3442428-B1 ONE STEP CARDIAC TEST DEVICE NOVAMED LTD (IL) 2022-03-02 EP claimed
CN-222851435-U Millimeter wave isolation transmission packaging structure 德氪微电子(深圳)有限公司 2025-05-09 CN disclosed
CN-222851436-U Millimeter wave isolation transmission packaging structure 德氪微电子(深圳)有限公司 2025-05-09 CN disclosed
CN-118888461-A Manufacturing method of millimeter wave isolation transmission packaging structure 德氪微电子(深圳)有限公司 2024-11-01 CN disclosed
CN-117535288-A lncRNA for inhibiting proliferation of hair follicle stem cells 西北农林科技大学 2024-02-09 CN disclosed
CN-116143839-A Water-soluble near infrared fluorescent molecular probe for detecting alkaline phosphatase as well as preparation method and application thereof 湖南超亟检测技术有限责任公司 2023-05-23 CN disclosed
US-20130177994-A1 METHODS FOR QUANTITATIVE CHIRAL DETERMINATION OF THE d- AND l- ENANTIOMERS OF AMPHETAMINE AND METHAMPHETAMINE CLINICAL REFERENCE LABORATORY, INC. (US) 2013-07-11 US disclosed
WO-2013103841-A1 METHODS FOR QUANTITATIVE CHIRAL DETERMINATION OF THE d- AND l- ENANTIOMERS OF AMPHETAMINE AND METHAMPHETAMINE CLINICAL REFERENCE LABORATORY, INC. (US) 2013-07-11 WO disclosed
US-5380654-A Process for the preparation of epoxides of means of microorganisms JAPAN ENERGY CORPORATION (JP) 1995-01-10 US disclosed
US-5376539-A Aerobic incubation of allyl phenyl ether with arthrobacter, brevibacterium, corynebacterium, pseudomonas or rhodococcus yields glycidyl phenyl ether NIPPON MINING CO., LTD. (JP) 1994-12-27 US disclosed
EP-0166527-B1 A PROCESS FOR THE PREPARATION OF EPOXIDES BY MEANS OF MICROORGANISMS NIPPON MINING COMPANY LIMITED (JP) 1991-04-03 EP disclosed
EP-0166527-A2 A process for the preparation of epoxides by means of microorganisms NIPPON MINING COMPANY LIMITED (JP) 1986-01-02 EP disclosed
US-4091029-A RESOLVING AGENT FOR RACEMIC MIXTURES ELI LILLY AND COMPANY (US) 1978-05-23 US disclosed
US-3972925-A RESOLUTION AGENT ELI LILLY AND COMPANY (US) 1976-08-03 US disclosed