Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 6/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11650731 | 0.94 | LMNA (0.53) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL11650734 | 0.94 | LMNA (0.53) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL7380987 | 0.80 | LMNA (0.58) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL1681430 | 0.80 | LMNA (0.58) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL1681427 | 0.80 | LMNA (0.58) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL9256608 | 0.79 | LMNA (0.38) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL11649747 | 0.79 | HSD17B10 (0.38) | LMNACYP2C19HSD17B10ACE | |
| Hydrochloric Acid SCHEMBL6325863 | 0.78 | LMNA (0.57) | LMNACYP2C19HSD17B10ACE | |
| Hydrochloric Acid SCHEMBL6325860 | 0.78 | LMNA (0.57) | LMNACYP2C19HSD17B10ACE | |
| SCHEMBL3709711 | 0.75 | LMNA (0.53) | LMNACYP2C19HSD17B10ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1537230-A4 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORP (US) | 2008-06-18 | — | — | EP | disclosed |
| CN-1697880-A | Fluorogenic enzyme assay methods and compositions | APPLERA CORP (US) | 2005-11-16 | — | — | CN | disclosed |
| EP-1537230-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | Applera Corporation (US) | 2005-06-08 | — | — | EP | disclosed |
| US-20040146959-A1 | Fluorescent enzyme assay methods and compositions | APPLIED BIOSYSTEMS, LLC | 2004-07-29 | — | — | US | disclosed |
| WO-2004022773-A1 | FLUORESCENT ENZYME ASSAY METHODS AND COMPOSITIONS | APPLERA CORPORATION (US) | 2004-03-18 | — | — | WO | disclosed |