Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBOAT4 | Q96T53 | 10/20 | 0.37 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.34 |
| ▸ | SLC33A1 | O00400 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256614 | 0.86 | SLC33A1 (0.34) | SLC33A1 | |
| SCHEMBL7311768 | 0.84 | PPARG (0.46) | ENPP1SLC33A1 | |
| SCHEMBL9256542 | 0.83 | ENPP1 (0.36) | MBOAT4ENPP1SLC33A1 | |
| SCHEMBL9254265 | 0.83 | MBOAT4 (0.35) | MBOAT4ENPP1SLC33A1HTT | |
| SCHEMBL9254410 | 0.82 | MBOAT4 (0.35) | MBOAT4ENPP1SLC33A1HTT | |
| Diethylamine SCHEMBL9256272 | 0.81 | PPARG (0.44) | ENPP1SLC33A1 | |
| SCHEMBL9257114 | 0.80 | SLC33A1 (0.34) | ENPP1SLC33A1 | |
| SCHEMBL9256663 | 0.79 | PPARG (0.43) | SLC33A1 | |
| SCHEMBL9253827 | 0.76 | PPARG (0.41) | MBOAT4ENPP1SLC33A1HTT | |
| SCHEMBL9308253 | 0.75 | PPARG (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |