Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | MBOAT4 | Q96T53 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SLC33A1 | O00400 | 4/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311768 | 0.87 | PPARG (0.46) | ENPP1SLC33A1PPARG | |
| Diethylamine SCHEMBL9256272 | 0.84 | PPARG (0.44) | ENPP1SLC33A1PPARG | |
| SCHEMBL9256622 | 0.83 | MBOAT4 (0.37) | ENPP1MBOAT4SLC33A1 | |
| SCHEMBL9254265 | 0.82 | MBOAT4 (0.35) | ENPP1MBOAT4SLC33A1 | |
| SCHEMBL9256663 | 0.82 | PPARG (0.43) | SLC33A1PPARG | |
| SCHEMBL9254410 | 0.80 | MBOAT4 (0.35) | ENPP1MBOAT4SLC33A1 | |
| SCHEMBL9251346 | 0.79 | SLC33A1 (0.37) | SLC33A1 | |
| SCHEMBL9253827 | 0.79 | PPARG (0.41) | ENPP1GABRA1GABRG2GABRB3GABRA2 | |
| SCHEMBL9254569 | 0.77 | ESR2 (0.40) | ENPP1GABRA1GABRG2GABRB3GABRA2 | |
| SCHEMBL9250470 | 0.77 | SLC33A1 (0.45) | ENPP1SLC33A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |