SCHEMBL9256668

SCHEMBL9256668

COc1ccc(OC)c(/C=C/C(=O)Cl)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JUN P05412 1/20 0.77
NFKB1 P19838 1/20 0.77
ABCG2 Q9UNQ0 1/20 0.70
PDE4A P27815 1/20 0.67
PDE4B Q07343 1/20 0.67
PDE4C Q08493 1/20 0.67
PDE4D Q08499 1/20 0.67
MAPT P10636 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
KDM4E B2RXH2 2/20 0.66
LMNA P02545 1/20 0.66
ATM Q13315 1/20 0.66
SMN1; SMN2 Q16637 1/20 0.66
TDP1 Q9NUW8 1/20 0.62
CYP1A1 P04798 2/20 0.58
CYP1B1 Q16678 2/20 0.58
CYP1A2 P05177 1/20 0.58
NFE2L2 Q16236 1/20 0.58
ALDH1A1 P00352 2/20 0.58
MEN1 O00255 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9256671 1.00 JUN (0.77) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL15163796 0.89 JUN (0.66) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL28312330 0.87 MAPT (0.77) JUNNFKB1MAPTL3MBTL1KDM4E
SCHEMBL28864077 0.87 MAPT (0.77) JUNNFKB1MAPTL3MBTL1KDM4E
SCHEMBL5598600 0.87 JUN (1.00) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL5598598 0.87 JUN (1.00) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL29814346 0.85 JUN (0.79) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL529638 0.85 JUN (0.79) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL10469552 0.85 JUN (0.79) JUNNFKB1ABCG2PDE4APDE4B
SCHEMBL10469550 0.85 JUN (0.79) JUNNFKB1ABCG2PDE4APDE4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020108481-A1 THIAMINE COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITION THEREOF 上海日馨生物科技有限公司 2020-06-04 WO disclosed
US-9171961-B2 Coating materials for oxide thin film transistors POLYERA CORPORATION (US) 2015-10-27 US disclosed
US-20140021465-A1 Coating Materials for Oxide Thin Film Transistors FLEXTERRA, INC. 2014-01-23 US disclosed
WO-2014011935-A1 COATING MATERIALS FOR OXIDE THIN FILM TRANSISTORS POLYERA CORPORATION (US) 2014-01-16 WO disclosed
US-5432173-A Psychological disorders ADIR ET COMPAGNIE (FR) 1995-07-11 US disclosed
US-4883653-A PLASTICS AND COSMETICS, SUNSCREENS OLIN CORPORATION (US) 1989-11-28 US disclosed