Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716720 | 0.89 | CES2 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL258682 | 0.89 | CES2 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL29919382 | 0.87 | CES2 (0.36) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL368571 | 0.87 | CES2 (0.36) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL8986519 | 0.82 | CES2 (0.33) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL516276 | 0.74 | CA9 (0.37) | HSD17B10KDM4EMAPTAPEX1RAD52 | |
| Trifluoroacetic Acid SCHEMBL7263980 | 0.73 | CES1 (0.37) | HSD17B10KDM4EMAPTTDP1L3MBTL1 | |
| SCHEMBL5509678 | 0.73 | CES2 (0.38) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL4685053 | 0.72 | CA1 (0.34) | ADRA2AADRA2BADRA2CADRA1AADRB2 | |
| SCHEMBL30786719 | 0.72 | HSD17B10 (0.40) | ADRA2AADRA2BADRA2CADRA1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511385-B1 | THERMOPLASTIC GRAFT COPOLYMER AND PRODUCTION THEREOF | SUMITOMO CHEMICAL CO (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5376730-A | Grafting an aromatic carboxy oligomer to an addition polymer; heat resistant hoses, seals | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-12-27 | — | — | US | disclosed |
| EP-0511385-A1 | THERMOPLASTIC GRAFT COPOLYMER AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-11-04 | — | — | EP | disclosed |