SCHEMBL258682

SCHEMBL258682

Oc1cc(F)c(F)c(F)c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.38
CES1 P23141 2/20 0.38
CA9 Q16790 2/20 0.38
CA3 P07451 1/20 0.38
CA6 P23280 1/20 0.38
CA5A P35218 1/20 0.38
CA14 Q9ULX7 1/20 0.38
CA5B Q9Y2D0 1/20 0.38
CA1 P00915 4/20 0.35
CA2 P00918 3/20 0.35
CA4 P22748 2/20 0.35
CA12 O43570 2/20 0.35
CA7 P43166 1/20 0.35
CA13 Q8N1Q1 1/20 0.35
ADRA2A P08913 2/20 0.34
ADRA2B P18089 2/20 0.34
ADRA2C P18825 2/20 0.34
ADRA1A P35348 2/20 0.34
ADRB2 P07550 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29716720 1.00 CES2 (0.38) CES2CES1CA9CA3CA6
SCHEMBL29919382 0.97 CES2 (0.36) CES2CES1CA9CA3CA6
SCHEMBL368571 0.97 CES2 (0.36) CES2CES1CA9CA3CA6
SCHEMBL8986519 0.92 CES2 (0.33) CES2CES1CA9CA3CA6
Chloroform SCHEMBL9256697 0.89 ADRA2A (0.34) CES2CES1CA9CA3CA6
SCHEMBL516276 0.83 CA9 (0.37) CES2CES1CA9CA3CA6
Trifluoroacetic Acid SCHEMBL7263980 0.82 CES1 (0.37) CES2CES1CA9CA3CA6
SCHEMBL5509678 0.81 CES2 (0.38) CES2CES1CA9CA3CA6
SCHEMBL67874 0.79 CA3 (0.36) CA9CA3CA6CA5ACA14
SCHEMBL515819 0.79 CES2 (0.36) CES2CES1CA9CA3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12606575-B2 Method for synthesizing zirconium complex JFE ENGINEERING CORPORATION (JP) 2026-04-21 US claimed
EP-4678240-A2 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES Hangzhou Dac Biotech Co., Ltd. (CN) 2026-01-14 EP claimed
EP-3319936-B1 BRIDGE LINKERS FOR CONJUGATION OF CELL-BINDING MOLECULES HANGZHOU DAC BIOTECH CO LTD (CN) 2025-12-17 EP claimed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 US claimed
US-20250361399-A1 FLUORESCENT DYES WITH LARGE STOKES SHIFT ROCHE MOLECULAR SYSTEMS INC (US) 2025-11-27 US claimed
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-11-18 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642484-A1 TARGETED TREATMENT OF PROSTATE CANCERS AND OTHER TUMORS BY AN ANTIBODY-DRUG CONJUGATE Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-10-07 US claimed
US-12351890-B2 Method for synthesizing zirconium complex JFE ENGINEERING CORPORATION (JP) 2025-07-08 US claimed
US-4956276-A FORMATION OF FLUORIDE ION FROM FLUORINATED AROMATIC COMPOUMD IN THE PRESENCE OF OXYGEN AND PEROXIDASE BATTELLE MEMORIAL INSTITUTE (CH) 1990-09-11 US claimed
EP-0384769-A2 Protein labelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1990-08-29 EP claimed
US-4937186-A Method for the determination of bilirubin in solution SCHIAPPARELLI BIOSYSTEMS, INC. 1990-06-26 US claimed
EP-0215824-B1 ANALYTIC METHOD FOR THE DETERMINATION OF A REDUCED COENZYME Pharmacia ENI Diagnostics Inc. (US) 1990-01-03 EP claimed
WO-1989007153-A1 A METHOD FOR THE DETERMINATION OF BILIRUBIN IN SOLUTION ELECTRO-NUCLEONICS, INC. (US) 1989-08-10 WO claimed
EP-0326524-A2 A method for the determination of bilirubin in solution SCHIAPPARELLI BIOSYSTEMS, INC. (US) 1989-08-02 EP claimed
EP-0160379-B1 2,3,5,6-TETRAFLUOROPHENYL (METH)ACRYLATES AND THEIR PRODUCTION Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1988-06-29 EP claimed
EP-0215824-A1 ANALYTIC METHOD FOR THE DETERMINATION OF A REDUCED COENZYME. BATTELLE MEMORIAL INSTITUTE (CH) 1987-04-01 EP claimed
WO-1986005517-A1 ANALYTIC METHOD FOR THE DETERMINATION OF A REDUCED COENZYME BATTELLE MEMORIAL INSTITUTE (CH) 1986-09-25 WO claimed
EP-0160379-A1 2,3,5,6-tetrafluorophenyl (meth)acrylates and their production Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) 1985-11-06 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606575-B2 Method for synthesizing zirconium complex CA1, TFRC, CA7 CES2 1927/4885CES1 2003/4885CA9 13/4885
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES FCGR2A, FCGR3B, FCGR1A CES2 829/4885CES1 1195/4885CA9 179/4885
US-12433950-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM CES2 346/4885CES1 1367/4885CA9 1674/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM CES2 346/4885CES1 1367/4885CA9 1674/4885
US-12472265-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM CES2 346/4885CES1 1367/4885CA9 1674/4885
US-12351890-B2 Method for synthesizing zirconium complex ZFP3, SLC39A3, SLC30A7 CES2 4510/4885CES1 3857/4885CA9 128/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.