Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 18/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | BCHE | P06276 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261176 | 1.00 | ACHE (0.65) | ACHEKMT2ANPSR1BCHE | |
| SCHEMBL9252949 | 1.00 | ACHE (0.65) | ACHEKMT2ANPSR1BCHE | |
| SCHEMBL9257375 | 0.91 | TP53 (0.56) | ACHEKMT2ANPSR1BCHE | |
| SCHEMBL10699056 | 0.86 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9259449 | 0.86 | ACHE (0.69) | ACHEKMT2ABCHE | |
| SCHEMBL9255955 | 0.86 | ACHE (0.69) | ACHEKMT2ABCHE | |
| Hydrochloric Acid SCHEMBL9261293 | 0.85 | ACHE (0.68) | ACHEKMT2ABCHE | |
| Hydrochloric Acid SCHEMBL9261956 | 0.85 | ACHE (0.68) | ACHEKMT2ABCHE | |
| SCHEMBL9260330 | 0.84 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL9257120 | 0.80 | ACHE (0.60) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |