Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 14/20 | 0.55 |
| ▸ | BCHE | P06276 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256698 | 0.91 | ACHE (0.65) | ACHEBCHEKMT2ANPSR1 | |
| SCHEMBL9261176 | 0.91 | ACHE (0.65) | ACHEBCHEKMT2ANPSR1 | |
| SCHEMBL9252949 | 0.91 | ACHE (0.65) | ACHEBCHEKMT2ANPSR1 | |
| SCHEMBL9257120 | 0.88 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL10699056 | 0.84 | ACHE (0.60) | ACHEBCHE | |
| SCHEMBL9260330 | 0.82 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL9259449 | 0.79 | ACHE (0.69) | HTTACHEBCHEKMT2A | |
| SCHEMBL9255955 | 0.79 | ACHE (0.69) | HTTACHEBCHEKMT2A | |
| Hydrochloric Acid SCHEMBL9261293 | 0.78 | ACHE (0.68) | HTTACHEBCHEKMT2A | |
| Hydrochloric Acid SCHEMBL9261956 | 0.78 | ACHE (0.68) | HTTACHEBCHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | claimed |
| US-5391553-A | Increasing cholinergic functionin mammals | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-02-21 | — | — | US | disclosed |