Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.44 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21454987 | 0.80 | GAA (0.52) | CXCR2PLK1GAAPOLBADRA1D | |
| SCHEMBL20972350 | 0.79 | PLK1 (0.50) | CXCR2PLK1GAACLCN2MTNR1A | |
| SCHEMBL9256777 | 0.77 | CLCN2 (0.44) | CXCR2PLK1GAACLCN2KMT2A | |
| SCHEMBL14688165 | 0.76 | PLK1 (0.47) | PLK1GAAPOLBHSD17B10 | |
| SCHEMBL24603694 | 0.74 | GAA (0.62) | PLK1GAAKMT2AMEN1 | |
| SCHEMBL16884622 | 0.74 | KMT2A (0.47) | PLK1GAAPOLBKMT2A | |
| SCHEMBL28864326 | 0.73 | PLK1 (0.45) | PLK1GAAPOLBCLCN2KMT2A | |
| SCHEMBL21590264 | 0.72 | GAA (0.44) | CXCR2PLK1GAAADRA1DADRA1A | |
| SCHEMBL27573602 | 0.71 | CHRNB2 (0.49) | PLK1GAAKMT2AMEN1 | |
| SCHEMBL14648299 | 0.71 | L3MBTL1 (0.42) | PLK1GAAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672032-A1 | NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES | Astra Aktiebolag (SE) | 1995-09-20 | — | — | EP | disclosed |