Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9260415 | 0.89 | HSD17B10 (0.50) | LMNACYP1A2CHRM1HSD17B10CHRM3 | |
| SCHEMBL9287474 | 0.89 | HSD17B10 (0.50) | LMNACYP1A2CHRM1HSD17B10CHRM3 | |
| SCHEMBL8670521 | 0.84 | SMN1; SMN2 (0.48) | TSHRKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL7163448 | 0.84 | SMN1; SMN2 (0.48) | TSHRKMT2AALDH1A1CYP1A2MEN1 | |
| SCHEMBL9260958 | 0.84 | CYP1A2 (0.42) | LMNACYP1A2 | |
| SCHEMBL9260101 | 0.83 | STS (0.47) | CHRM1CHRM2CHRM3 | |
| SCHEMBL9262360 | 0.83 | CYP1A2 (0.41) | ALDH1A1CYP1A2RORCPOLB | |
| SCHEMBL9257570 | 0.80 | CYP1A2 (0.43) | KMT2AALDH1A1CYP1A2CHRM1 | |
| SCHEMBL9254630 | 0.79 | FOLH1 (0.41) | ALDH1A1CYP1A2RORCPOLB | |
| SCHEMBL9254625 | 0.79 | FOLH1 (0.41) | ALDH1A1CYP1A2RORCPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |