Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 5/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313501 | 0.91 | CYP3A4 (0.50) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9246899 | 0.86 | TTPA (0.43) | ALDH1A1MAPTSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL9313960 | 0.80 | TTPA (0.48) | MAPTKDM4EPTGS1PTGS2CYP1A2 | |
| SCHEMBL9257226 | 0.77 | PTGS1 (0.46) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8537690 | 0.77 | PTGS1 (0.53) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9254778 | 0.77 | BCHE (0.51) | KMT2AMEN1PTGS1PTGS2CYP1A2 | |
| SCHEMBL9258907 | 0.76 | PTGS1 (0.52) | MAPTKMT2AMEN1PTGS1PTGS2 | |
| SCHEMBL8542430 | 0.76 | PTGS1 (0.57) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8538124 | 0.75 | PTGS1 (0.53) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9265028 | 0.75 | PTGS1 (0.51) | MAPTKMT2AKDM4EMEN1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395834-A | Antiarthritic agents or cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1995-03-07 | — | — | US | disclosed |
| US-5393775-A | Administering a (2-chromanyl)alkylcarboxylic acid for disorders connected with peroxidation processes | ADIR ET COMPAGNIE (FR) | 1995-02-28 | — | — | US | disclosed |
| EP-0587499-A1 | Benzopyran compounds, process for their preparation and their use as cell protectors | ADIR ET COMPAGNIE (FR) | 1994-03-16 | — | — | EP | disclosed |