Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 12/20 | 0.48 |
| ▸ | ACHE | P22303 | 12/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256869 | 0.91 | ALDH1A1 (0.45) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9313960 | 0.89 | TTPA (0.48) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9246899 | 0.81 | TTPA (0.43) | CYP3A4TRPV1 | |
| SCHEMBL9689558 | 0.80 | PTGS1 (0.52) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9688177 | 0.80 | PTGS1 (0.60) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9312724 | 0.77 | PTGS1 (0.61) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9312883 | 0.76 | PTGS1 (0.54) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9656754 | 0.76 | PTGS1 (0.66) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9313643 | 0.76 | PTGS1 (0.66) | CYP3A4PTGS1PTGS2CYP1A2TSHR | |
| SCHEMBL9253766 | 0.76 | PTGS1 (0.66) | CYP3A4PTGS1PTGS2CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5315017-A | Peroxidation and eicosanoid biosynthesis inhibition | ADIR ET COMPAGNIE (FR) | 1994-05-24 | — | — | US | disclosed |
| EP-0512899-A1 | Benzopyran compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-11-11 | — | — | EP | disclosed |