Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 4/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9286651 | 0.83 | CYP1A2 (0.41) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9285312 | 0.80 | CYP1A2 (0.38) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9255783 | 0.77 | NPC1 (0.43) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9255787 | 0.77 | NPC1 (0.43) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9285323 | 0.74 | MAPT (0.37) | MAPTNPSR1CYP2C9APPSNCA | |
| SCHEMBL9256886 | 0.72 | CYP1A2 (0.49) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8880980 | 0.70 | MDM2 (0.40) | MAPTCES1 | |
| SCHEMBL31404120 | 0.65 | PDK2 (0.50) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2268820 | 0.65 | PDK2 (0.50) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6246169 | 0.65 | ALDH1A1 (0.43) | MAPTCYP1A2SMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018127-A1 | AZA-4-IMINOQUINOLINES, METHODS OF PREPARING THEM AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-06 | — | — | WO | disclosed |