SCHEMBL9256922

SCHEMBL9256922

CCCCc1c(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)c(O)nc2nc(C)nn12

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC33A1 O00400 5/20 0.43
AGTR1 P30556 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7932757 0.87 SLC33A1 (0.45) SLC33A1AGTR1
SCHEMBL9258615 0.86 SLC33A1 (0.39) SLC33A1
SCHEMBL9247526 0.86 SLC33A1 (0.38) SLC33A1
SCHEMBL7310948 0.85
SCHEMBL9254131 0.85 SLC33A1 (0.37) SLC33A1
SCHEMBL9846014 0.82
SCHEMBL8314256 0.82 SLC33A1 (0.46) SLC33A1
SCHEMBL9257587 0.81 SLC33A1 (0.34) SLC33A1
SCHEMBL9256213 0.80 PPARG (0.43) SLC33A1AGTR1
SCHEMBL9255550 0.79 SLC33A1 (0.42) SLC33A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5387747-A Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis LABORATOIRES UPSA (FR) 1995-02-07 US disclosed