Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 15/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9263794 | 0.83 | HTT (0.40) | HTTCYP1A2POLBCYP2C19 | |
| SCHEMBL9263856 | 0.80 | HTT (0.38) | HTTCYP1A2POLBCYP2C19 | |
| SCHEMBL9262840 | 0.80 | SMN1; SMN2 (0.43) | MAP3K5HTTTDP1CYP1A2POLB | |
| SCHEMBL9255169 | 0.78 | CYP1A2 (0.43) | HTTCYP1A2CYP2C19 | |
| SCHEMBL9213645 | 0.77 | HTT (0.37) | HTTCYP1A2POLBCYP2C19 | |
| SCHEMBL9259026 | 0.75 | ADORA2A (0.38) | HTTCYP1A2CYP2C19MAPT | |
| SCHEMBL9256348 | 0.73 | MAPK1 (0.46) | HTTCYP1A2CYP2C19MAPT | |
| SCHEMBL9273126 | 0.72 | HTT (0.40) | HTTCYP1A2POLBCYP2C19 | |
| SCHEMBL9261024 | 0.72 | MAPT (0.39) | MAP3K5TDP1CYP1A2POLBCYP2C19 | |
| SCHEMBL10518789 | 0.70 | HTT (0.51) | HTTCYP1A2POLBCYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475000-A | Antiulcer agents | CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1995-12-12 | — | — | US | disclosed |
| EP-0641340-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO- 1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993004065-A1 | NEW 3-(SUBSTITUTED TETRAZOLYL)-4-OXO-4H-PYRIDO-[1,2-a]PYRIMIDINES, SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-03-04 | — | — | WO | disclosed |