Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | KCNQ3 | O43525 | 3/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451093 | 0.85 | HTT (0.70) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL230029 | 0.83 | RAB9A (0.50) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL311361 | 0.83 | HTT (0.71) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL1356474 | 0.82 | MAPT (0.57) | HTTMAPK1RAB9AKDM4EALDH1A1 | |
| SCHEMBL23706586 | 0.80 | PPARG (0.55) | HTTLMNAKDM4EALDH1A1MAPT | |
| SCHEMBL7214442 | 0.80 | KDM4E (0.47) | HTTLMNAMAPK1RAB9AKDM4E | |
| SCHEMBL17355761 | 0.78 | RAB9A (0.43) | HTTLMNAMAPK1RAB9AKDM4E | |
| SCHEMBL15290724 | 0.76 | LMNA (0.47) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL17356420 | 0.75 | MRGPRX4 (0.46) | HTTLMNAMAPK1RAB9ATAS1R3 | |
| SCHEMBL17356412 | 0.74 | CYP2C19 (0.47) | HTTKDM4EALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5422037-A | For electro-optical and display devices | DISPLAYTECH, INC. (US) | 1995-06-06 | — | — | US | disclosed |
| US-5180520-A | Ferroelectric liquid crystal compositions containing halogenated cores and chiral halogenated cores and chiral haloalkoxy tail units | UNIVERSITY RESEARCH CORPORATION (US) | 1993-01-19 | — | — | US | disclosed |
| WO-1992001766-A1 | FERROELECTRIC LIQUID CRYSTAL COMPOSITIONS CONTAINING HALOGENATED CORES AND CHIRAL HALOALKOXY TAIL UNITS | DISPLAYTECH, INC. (US) | 1992-02-06 | — | — | WO | disclosed |