SCHEMBL9256988

SCHEMBL9256988

O=C(CF)c1cscc1Br

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 3/20 0.38
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8836807 0.79 GSK3B (0.38) GSK3BCTSLCTSBCTSS
SCHEMBL2778839 0.73
SCHEMBL7204207 0.71
SCHEMBL1786898 0.71
SCHEMBL3854074 0.71
SCHEMBL12430466 0.68 ALDH1A1 (0.50)
SCHEMBL7224999 0.67 SMN1; SMN2 (0.39) CTSLCTSBCTSS
SCHEMBL1527656 0.67 TSHR (0.39) GSK3B
SCHEMBL2352202 0.67 ALDH1A1 (0.42) GSK3B
SCHEMBL21677179 0.64 SMN1; SMN2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5461024-A Herbicides KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1995-10-24 US disclosed
EP-0575435-A1 THIOPHENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1993-12-29 EP disclosed
WO-1992016525-A1 THIOPHENESULFONYLUREA DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1992-10-01 WO disclosed