Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.68 |
| ▸ | TNF | P01375 | 1/20 | 0.62 |
| ▸ | GALR3 | O60755 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.61 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.57 |
| ▸ | PTAFR | P25105 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3668391 | 0.89 | HDAC1 (0.73) | HDAC1HDAC6TNFGALR3RAB9A | |
| SCHEMBL6169424 | 0.85 | TNF (0.56) | HDAC1HDAC6TNFRAB9AALDH1A1 | |
| SCHEMBL9335680 | 0.84 | PTAFR (0.60) | PTAFR | |
| SCHEMBL1331422 | 0.84 | HDAC1 (0.74) | HDAC1HDAC6TNFGALR3RAB9A | |
| SCHEMBL9087920 | 0.84 | AGTR1 (0.76) | DRD2TBXA2RAGTR1AGTR2 | |
| SCHEMBL6168941 | 0.84 | PDE2A (0.56) | HDAC1HDAC6TNFRAB9ADRD2 | |
| SCHEMBL6169712 | 0.84 | HDAC1 (0.52) | HDAC1HDAC6TNFGALR3RAB9A | |
| SCHEMBL6170856 | 0.84 | HDAC1 (0.52) | HDAC1HDAC6TNFRAB9ADRD2 | |
| Hydrochloric Acid SCHEMBL3500155 | 0.83 | HDAC1 (0.73) | HDAC1HDAC6TNFGALR3RAB9A | |
| SCHEMBL9302226 | 0.83 | HDAC1 (0.73) | HDAC1HDAC6TNFGALR3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428168-A | Substituted butyrolactol ether derivative | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-06-27 | — | — | US | disclosed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0527817-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1993-02-24 | — | — | EP | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1991017157-A1 | GAMMA-BUTYROLACTOL ETHER DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1991-11-14 | — | — | WO | disclosed |