Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.73 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.73 |
| ▸ | TNF | P01375 | 1/20 | 0.71 |
| ▸ | GALR3 | O60755 | 2/20 | 0.66 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | PTAFR | P25105 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331422 | 0.90 | HDAC1 (0.74) | HDAC1HDAC6TNFGALR3NR2F2 | |
| Hydrochloric Acid SCHEMBL3500155 | 0.89 | HDAC1 (0.73) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL6170393 | 0.87 | HDAC1 (0.57) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL12850475 | 0.84 | HDAC1 (1.00) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL3668391 | 0.84 | HDAC1 (0.73) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL14000450 | 0.84 | HDAC1 (0.81) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL231295 | 0.84 | TNF (1.00) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL9302136 | 0.84 | HDAC1 (0.72) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL9256992 | 0.83 | HDAC1 (0.68) | HDAC1HDAC6TNFGALR3NR2F2 | |
| SCHEMBL6169712 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6TNFGALR3NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | claimed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | claimed |
| US-5314880-A | Platelet activating factor antagonist | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1994-05-24 | — | — | US | disclosed |
| EP-0468971-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990009997-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1990-09-07 | — | — | WO | disclosed |