Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.43 |
| ▸ | GCGR | P47871 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249609 | 0.91 | HDAC1 (0.52) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9247609 | 0.90 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| Bromide SCHEMBL9253343 | 0.89 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9255709 | 0.85 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9252223 | 0.85 | HDAC6 (0.54) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9249490 | 0.84 | HDAC1 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9257052 | 0.83 | HDAC1 (0.54) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9251347 | 0.82 | HDAC1 (0.50) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9251361 | 0.82 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL9254127 | 0.81 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | disclosed |